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Although the role of apelin and APJ receptor in
2024-06-06

Although the role of apelin and APJ receptor in cardiovascular functions has been well-elucidated, little is known for the effect of the central apelinergic system on gastrointestinal (GI) functions. In mice, it has been found previously that central exogenous apelin-13 decreased gastric emptying (G
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During the course of angiogenesis the overactivated angiogen
2024-06-06

During the course of angiogenesis, the overactivated angiogenic stimulators are responsible for carrying out abnormal proliferation in the retinal microvasculature, resulting in the formation of various immature blood vessels. These newly formed blood vessels become the prime spots for leakage of th
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Akt is another upstream kinase known to
2024-06-06

Akt is another upstream kinase known to phosphorylate AMPK Ser489 in response to high insulin levels [7], [21]. HepG2 2-APB show an increase in phosphorylation of AMPK at Ser485 when incubated with either insulin or troglitazone individually (Fig. 5A and C). Despite this concurrent increase, only c
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prostaglandin receptor Our present result that week old PKA
2024-06-06

Our present result that ≤2-week-old 150ΔPKA mice express normal LTP that does not depend on CP-AMPARs also supports the collective findings of previous work showing that LTP mechanisms are remarkably adaptable in juvenile animals compared with adults. In particular, GluA1 knockout, S845A/S831A, and
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When arachidonic acid is used as a substrate the
2024-06-06

When arachidonic vasopressin receptor antagonists is used as a substrate, the platelet-type 12S-lipoxygenase produces predominantly the 12S-hydroperoxy derivative. In contrast, the leukocyte-type 12S-lipoxygenases generate substantial amounts of the 15-lipoxygenase product in addition to the 12S-hy
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The reactions and the control mechanisms described are all s
2024-06-06

The reactions and the control mechanisms described are all supported by observations. For example the reactions require that different compounds are formed in different groups of U 46619 cells and this has been observed [15]. Intravenous injection of glycine results in reduced utilisation of glucos
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Therefore to better understand the functional properties of
2024-06-06

Therefore, to better understand the functional properties of Peruvian infusion tea plants and provide evidence for the development of functional food supplements containing the Peruvian infusion tea plant, the aldose reductase inhibition together with the antioxidant activities of 24 selected Peruvi
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Di ethylhexyl phthalate DEHP is one
2024-06-06

Di-(2-ethylhexyl) phthalate (DEHP) is one of the most widely used environmental chemicals in the production of polyvinyl chloride. After YT Broth, 2X powder blend into human body, DEHP can be converted to the metabolite mono-ethylhexyl phthalate (MEHP), which has higher toxicity than DEHP and can in
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br Parkinson s Disease and the
2024-06-06

Parkinson’s Disease and the immune system Parkinson’s Disease (PD) is the second most common neurodegenerative disorder, after Alzheimer’s, which affects 10 million people globally and is characterized by rigidity, bradykinesia, tremors, and gait instability (O’sullivan et al., 2007). The patholo
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The direction of glutamate transport by the
2024-06-06

The direction of glutamate transport by the cell membrane transporter is reversible. As mentioned above, glutamate transport is an electrogenic process associated with a transmembrane ion gradient established by the Na+-K+ pump through hydrolysis of adenosine triphosphate. Under conditions of energy
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In addition we aimed to examine the
2024-06-06

In addition, we aimed to examine the possible role of adiponectin in modulating changes in IR. It was observed that there was a simultaneous decline in expression of IR and AdipoR1 proteins in the ovary of PCOS-mice as compared to the control ovary. Further, a strong correlation was found between ch
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ADA catalyzes the deamination of adenosine and deoxyadenosin
2024-06-06

ADA catalyzes the deamination of adenosine and deoxyadenosine into their respective inosine nucleoside (Cristalli et al., 2001). This conversion is an initial step in a series of reactions responsible for lymphocyte proliferation and differentiation. Moreover, ADA is considered an indicator of cellu
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br Conflict of interest br Acknowledgments This work was sup
2024-06-06

Conflict of interest Acknowledgments This work was supported by research grant [PR26/20326] from Santander Bank/UCM. The authors would like to thank Miguel Capo, Professor of Toxicology from the Universidad Complutense de Madrid, for his counseling during the preparation of the present work.
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MnTBAP Chloride Language emerged among the Ach through
2024-06-06

“Language” emerged among the Aché through the influence of colonizers, missionaries, Bible translators, activists, anthropologists, the media, and the State. As an object, it now circulates in books, cellphones, political debates, at cultural events, on the radio, and even the Internet. It emerged a
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br Conclusions br Conflicts of interest br
2024-06-06

Conclusions Conflicts of interest Acknowledgements This work was supported by Ege University Research Fund [BAP, 14-ECZ-030, 2016]. Introduction The interest in the effects of endocrine disrupting chemicals (EDCs) in the aquatic environment continues to increase over the past decade, sp
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