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Bile acids are cholesterol derivatives produced only
2019-04-22

Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s
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Before the start of the study we
2019-04-22

Before the start of the study, we expected referral of up to 3% visceral leishmaniasis cases to the tertiary hospital for management of eventual complications. However, no referral was necessary because all adverse events were mild. Incidence of adverse events was about 47% during treatment and 63%
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amphetamine sulfate Much of the focus of expert and
2019-04-22

Much of the focus of expert and public attention has been on HIV treatment, including test and treat (ie, treatment as prevention) strategies. This is understandable. Treatment for HIV has become extraordinarily effective, costs have dropped substantially during the past two decades, and the potenti
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En raz n del desarrollo
2019-04-22

En razón del desarrollo que la oposición entre el individuo y la colectividad ha cobrado en Occidente, y cada vez es más aguda, se han entendido o malentendido las demandas de los pueblos indígenas como contrarias dna-pk inhibitor los derechos individuales, pero tal perspectiva es reduccionista, ya
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La Proclama se alaba que las Fuerzas armadas asum
2019-04-22

La “Proclama” señalaba que las Fuerzas armadas asumían la conducción del Estado con el propósito de “terminar con el desgobierno, la corrupción y el flagelo subversivo.” En Guatemala, el “Comunicado Urgente al Pueblo” inmediatamente después del golpe del 23 de marzo de 1982 decía que: “El ejército
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The patient refused either radiation therapy
2019-04-22

The patient refused either radiation therapy or systemic chemotherapy including rituximab and thus was initially treated with antibacterial therapy for HP infection. The first-line therapy consisted of lansoprazole 30mg, amoxicillin 750mg, and clarithromycin 200mg twice daily for 1 week. After 2 mon
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br Introduction Homocysteine Hcy is a
2019-04-22

Introduction Homocysteine (Hcy) is a sulfur-containing amino 3X FLAG Peptide that has a key role in methionine metabolism. Disturbance of this metabolic pathway may result in the accumulation of Hcy and related abnormal outcomes such as cognitive disorders, cancer, and birth defects. In particul
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br Outstanding questions br Conflict of interest br Acknowle
2019-04-20

Outstanding questions Conflict of interest Acknowledgments This work was supported by the Dutch Cancer SocietyUL2015-7599 KWF (EZ). Platelets and cancer metastasis Blood platelets play a primary role in wound healing and hemostasis. Since the first observation made (on himself) by the s
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Advani et al reported that CsA was associated
2019-04-20

Advani et al. reported that CsA was associated with good overall and durable responses. Although the mechanism remains unclear, CsA may inhibit the function of T cells, including their production of cytokines involved in the progression of AITL. Consequently, immunosuppressive therapies might exacer
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br Case report We report a case
2019-04-20

Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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An interphase FISH analysis with
2019-04-20

An interphase FISH analysis with BCR-ABL1-DCDF (dual colour dual fusion) probes (Abbott) showed a normal signal pattern. In addition, an RT-PCR screen with primers specific for the BCR-ABL1 p210 and p190 fusion transcripts and a JAK2V617F mutation analysis were both negative. Chromosomal analysis of
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br Conclusions br Acknowledgments We thank
2019-04-20

Conclusions Acknowledgments We thank webshop.elsevier.com for the assistance of the language-editing service. Introduction Sleep drives metabolite clearance from the adult Phenyl sulfate (Xie et al., 2013) and promotes learning-dependent synapse formation and maintenance of selected dendr
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Devemos destacar tamb m o
2019-04-19

Devemos destacar também o que entendemos por Intelectuais, ten-do como suporte para Bleomycin Sulfate construção do conceito os autores Carlos Altamirano e Jean-François Sirinelli. O termo intelectual, de acordo com Sirinelli, traz em si duas acepções de natureza sociocultural, sendo uma mais ampla,
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br In the past year migration to Europe
2019-04-19

In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm
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In this study the distribution of LPs was also
2019-04-19

In this study, the distribution of LPs was also analyzed. Similar to previously published data, there was a tendency that vLPs were more frequently observed in patients with ICM than in patients with NICM. However, the total number of those abnormal ventricular electrograms was less documented than
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