• The results described thus far suggest that

  2019-04-25

  

  The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the

• Many studies over the past

  2019-04-25

  

  Many studies over the past 20 years have shown the potential of urinary markers in the detection of the presence of bone metastases [3–11], the use of urinary markers for its prognostic value in bone disease [2,4,12–20], as well as directing therapy for bone metastases patients [2,6,12–18,21–25]. Th

• Our two groups of patients were similar in all

  2019-04-25

  

  Our two groups of patients were similar in all, but two, parameters: the non-inducible group had a significantly higher prevalence of atrial fibrillation (Table 1) and a significantly lower use of β-blockers at the time of enrollment into the study (discharge time after PES only or ICD implantation)

• In the present study the

  2019-04-24

  

  In the present study, the TACT measurement scores by EPS and TDI among women aged 20–30 were statistically and borderline significantly lower than in those aged 30–40. Similarly, men aged 20–30 years had lower scores than those aged 30–40. However, non-significant statistical differences were observ

• br Primary biliary cholangitis Primary biliary cholangitis

  2019-04-24

  

  Primary biliary cholangitis Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is another rare but devastating immune-mediated cholangiopathy. Similar to PSC, PBC is characterized by portal inflammation leading to fibrosis and eventually cirrhosis. Distinct from PSC

• cholesterol absorption inhibitors March marked annual World

  2019-04-24

  

  March 24 marked annual World TB Day, this year\'s theme being “reach the 3 million” who acquire tuberculosis every year but who do not get diagnosed, treated, or cured. Why do so many patients with this life-threatening infectious disease go under the radar? One reason, as Madhukar Pai and colleague

• br Malaria is a major

  2019-04-24

  

  Malaria is a major public health problem and a leading cause of mortality worldwide, especially in sub-Saharan Africa, where 90% of the world\'s 627 000 malaria deaths occur every year. However, the disease is usually curable if diagnosed quickly. Diagnosis is often made on the basis of clinical s

• br Raising taxes on tobacco is the

  2019-04-24

  

  Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2

• Las l neas le comunican a Felipe que l

  2019-04-24

  

  Las líneas le comunican Ponatinib Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Girón con

• Notwithstanding issues of equity improvement

  2019-04-23

  

  Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o

• In a previous report it

  2019-04-23

  

  In a previous report, it was speculated that withdrawal syndrome after IM cessation was related to a loss of blocking tyrosine kinases, such as c-kit and platelet-derived growth factor receptor (PDGFR) [2]. The inhibition of c-kit and PDGFR by IM reduces and increases the number of osteoclasts and o

• Skin involvement is present in of cases of fusariosis

  2019-04-23

  

  Skin involvement is present in 68–70% of cases of fusariosis [5]. As skin is one of the primary sources of entry, thorough skin examination and biopsy of suspicious nodules should be considered. Sinus involvement occurs in 80% of cases of disseminated fusariosis, with manifestations including facial

• A year old male with

  2019-04-23

  

  A 52-year-old male with known dextrocardia and CCTGA presented with a 2-month history of recurrent presyncope and effort intolerance. His examination revealed a resting pulse rate of 52beats/min (bpm) and a blood pressure of 130/80mmHg. The apex beat and heart sounds were appreciated on the right si

• Recently emerging data suggest that lower frequency

  2019-04-22

  

  Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f

• The standard therapy for chordoma is excision Local

  2019-04-22

  

  The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c

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